Design
Review
Key result
Tissue-specific expression of lipoprotein lipase is the rate-limiting process for triglyceride-derived fatty acid uptake, with imbalances having major metabolic consequences like obesity resistance.
Authors
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Targeting tissue-specific LPL may offer metabolic avenues; extends prior regulation data but leaves clinical adoption open.
Lipoprotein lipase plays a central role in energy metabolism, and targeting its tissue-specific expression pattern may offer new therapeutic avenues for metabolic and atherosclerotic diseases.
Preiss-Landl et al. (2002) conducted a review in Lipid and energy metabolism. Tissue-specific expression of lipoprotein lipase is the rate-limiting process for triglyceride-derived fatty acid uptake, with imbalances having major metabolic consequences like obesity resistance.
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