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February 13, 2010Journal of Hypertension

Consequences of orthostatic blood pressure variability in middle-aged men (The Malmö Preventive Project)

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Why the study?

Does orthostatic hypotension increase the risk of incident coronary events, stroke, and all-cause mortality in middle-aged men?

Population

5,722 middle-aged men (mean age 52.6 +/- 3.6 years) from the Malmö Preventive Project

Comparison

Orthostatic hypotension at re-screening or… vs Men without orthostatic hypotension

Design

Cohort

Follow-up

19.6 +/- 5.3 years

Authors

AFArtur FedorowskiLSLars StavenowBHBo Hedblad

Discussion

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Overview

Persistent orthostatic hypotension may identify middle-aged men for closer monitoring; leaves open whether screening or intervention improves outcomes.

Structured PICO

Does orthostatic hypotension increase the risk of incident coronary events, stroke, and all-cause mortality in middle-aged men?

P
Population
5,722 middle-aged men (mean age 52.6 +/- 3.6 years) from the Malmö Preventive Project
I
Intervention
Orthostatic hypotension (OH) at re-screening or persistent OH (at baseline and re-screening)
C
Comparator
Men without orthostatic hypotension
O
Outcome
Incident coronary event, stroke, and all-cause mortalityhard clinical

Orthostatic hypotension is an independent cardiovascular risk factor in middle-aged men, with persistent orthostatic hypotension conferring the highest risk of adverse events.

Cite This Study

Fedorowski et al. (2010) studied this question.

synapsesocial.com/papers/6a19c4663e4c9aaeb7f66530https://doi.org/10.1097/hjh.0b013e3283350e8c
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