What does this research mean for the field?

Women with polycystic ovary syndrome have a substantially higher than expected prevalence of impaired glucose tolerance and diabetes, as well as an accelerated conversion rate from impaired glucose tolerance to diabetes. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 1999Diabetes Care

Glucose tolerance was abnormal in 45% of women (35% IGT, 10% NIDDM), and in the follow-up subset, 2-h glucose significantly increased from 139 +/- 6 to 161 +/- 9 mg/dl (P < 0.02).

View Full Paper

Ask AI

Bookmark

Why the study?

What is the prevalence and natural history of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome?

Population

122 women with clinical and hormonal evidence of polycystic ovary syndrome recruited from the University of…

Design

Cohort

Follow-up

mean 2.4 +/- 0.3 years for the follow-up subset

Authors

DEDavid A. Ehrmann RBRandall B. Barnes RRRobert L. Rosenfield

Discussion

Member takes

Overview

High glucose intolerance prevalence and progression in PCOS supports vigilance; extends prior NIDDM links but leaves optimal screening open.

Structured PICO

What is the prevalence and natural history of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome?

Population

122 women with clinical and hormonal evidence of polycystic ovary syndrome (PCOS) recruited from the University of Chicago.

Intervention

Standard oral glucose tolerance test (OGTT) with measurement of glucose and insulin levels, with a subset of 25 women restudied to characterize natural history.

Outcome

Prevalence and incidence of glucose intolerance (impaired glucose tolerance and NIDDM).surrogate

Women with PCOS have a high prevalence of impaired glucose tolerance and diabetes, with accelerated progression, indicating a need for periodic OGTT monitoring.

Cite This Study

Ehrmann et al. (1999) studied this question.

synapsesocial.com/papers/6a19cd6305af093a17f694c4 https://doi.org/10.2337/diacare.22.1.141

View Full Paper

Ask AI

Bookmark

January 1, 1999Diabetes Care

Glucose tolerance was abnormal in 45% of women (35% IGT, 10% NIDDM), and in the follow-up subset, 2-h glucose significantly increased from 139 +/- 6 to 161 +/- 9 mg/dl (P < 0.02).

View Full Paper

Ask AI

Bookmark

Why the study?

What is the prevalence and natural history of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome?

Population

122 women with clinical and hormonal evidence of polycystic ovary syndrome recruited from the University of…

Design

Cohort

Follow-up

mean 2.4 +/- 0.3 years for the follow-up subset

Authors

DEDavid A. Ehrmann RBRandall B. Barnes RRRobert L. Rosenfield

Discussion

Member takes

Overview

High glucose intolerance prevalence and progression in PCOS supports vigilance; extends prior NIDDM links but leaves optimal screening open.

Structured PICO

What is the prevalence and natural history of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome?

Population

122 women with clinical and hormonal evidence of polycystic ovary syndrome (PCOS) recruited from the University of Chicago.

Intervention

Standard oral glucose tolerance test (OGTT) with measurement of glucose and insulin levels, with a subset of 25 women restudied to characterize natural history.

Outcome

Prevalence and incidence of glucose intolerance (impaired glucose tolerance and NIDDM).surrogate

Women with PCOS have a high prevalence of impaired glucose tolerance and diabetes, with accelerated progression, indicating a need for periodic OGTT monitoring.

Cite This Study

Ehrmann et al. (1999) studied this question.

synapsesocial.com/papers/6a19cd6305af093a17f694c4 https://doi.org/10.2337/diacare.22.1.141

View Full Paper

Ask AI

Bookmark