Simultaneous multislice spiral perfusion at multiband factors 2, 3, and 4 produced high-quality images (scores 4.2-4.4 out of 5) with no significant difference in quality between factors (P=0.38).
Does a simultaneous multislice (SMS) spiral perfusion pulse sequence provide high-quality whole-heart myocardial perfusion imaging compared to standard imaging?
Simultaneous multislice spiral perfusion imaging at multiband factors 2, 3, and 4 produces high-quality whole-heart perfusion images comparable to standard imaging.
p-value: p=0.38
PURPOSE: To develop and evaluate a simultaneous multislice (SMS) spiral perfusion pulse sequence with whole-heart coverage. METHODS: An orthogonal set of phase cycling angles following a Hadamard pattern was incorporated into a golden-angle (GA) variable density spiral perfusion sequence to perform SMS imaging at different multiband (MB) factors. Images were reconstructed using an SMS extension of L1-SPIRiT that we have termed SMS-L1-SPIRiT. The proposed sequence was evaluated in 40 subjects (10 each for MB factors of 1, 2, 3, and 4). Images were blindly graded by 2 cardiologists on a 5-point scale (5, excellent). To quantitatively evaluate the reconstruction performance against images acquired without SMS, the MB =1 data were used to retrospectively simulate data acquired at MB factors of 2 to 4. RESULTS: Analysis of the SMS point-spread function for the desired slice showed that the proposed sampling strategy significantly canceled the main-lobe energy of the other slices and has low side-lobe energy resulting in an incoherent temporal aliasing pattern when rotated by the GA. Retrospective experiments demonstrated the SMS-L1-SPIRiT method removed aliasing from the interfering slices and showed excellent agreement with the ground-truth MB =1 images. Clinical evaluation demonstrated high-quality perfusion images with average image-quality scores of 4.3 ± 0.5 (MB =2), 4.2 ± 0.5 (MB =3), and 4.4 ± 0.4 (MB =4) with no significant quality difference in image quality between MB factors (P = 0.38). CONCLUSION: SMS spiral perfusion at MB factors 2, 3, and 4 produces high-quality perfusion images with whole-heart coverage in a clinical setting with high sampling efficiency.
Yang et al. (Fri,) reported a other. Simultaneous multislice (SMS) spiral perfusion pulse sequence vs. Images acquired without SMS (MB=1) was evaluated on Image quality score on a 5-point scale (p=0.38). Simultaneous multislice spiral perfusion at multiband factors 2, 3, and 4 produced high-quality images (scores 4.2-4.4 out of 5) with no significant difference in quality between factors (P=0.38).
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