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December 1, 2003Radiology

Heart Failure: Evaluation of Cardiopulmonary Transit Times with Time-resolved MR Angiography

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Why the study?

Does time-resolved MR angiography accurately measure cardiopulmonary transit times and correlate with conventional MR indexes of cardiac function in patients with heart failure?

Population

26 patients with heart failure and left ventricular systolic dysfunction and 13 control subjects

Comparison

Low-dose, time-resolved magnetic resonance… vs Control subjects without heart failure

Design

Case-control

Authors

SSStephanie M. ShorsWCWilliam CottsBPBiljana Pavlovic-Surjancev

Discussion

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Overview

Transit times associate with LV dysfunction in heart failure on MR angiography; leaves open prospective validation for clinical use.

Structured PICO

Does time-resolved MR angiography accurately measure cardiopulmonary transit times and correlate with conventional MR indexes of cardiac function in patients with heart failure?

P
Population
26 patients with heart failure and left ventricular (LV) systolic dysfunction (17 men, 9 women; age range 22-78 years) and 13 control subjects (8 men, 5 women; age range 23-59 years)
I
Intervention
Low-dose, time-resolved magnetic resonance (MR) angiography and rapid cine MR imaging
C
Comparator
Control subjects without heart failure
O
Outcome
Cardiopulmonary transit times and dispersions (full widths at half maximum [FWHM])surrogate

Time-resolved MR angiography can determine cardiopulmonary transit times, which are prolonged in heart failure and correlate with LV volumes and ejection fraction.

Cite This Study

Shors et al. (2003) studied this question.

synapsesocial.com/papers/6a1a77f849c3147e1045ab9chttps://doi.org/10.1148/radiol.2293021363
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