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May 31, 2026Journal of Sleep ResearchOpen Access

COVID ‐19–Induced Narcolepsy Type I With Cataplexy: A Short Report

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Authors

TMTorsten Vinding MerinderMLMartin Langeskov‐ChristensenFKFilip Kirov

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Overview

Case report reveals narcolepsy type I with cataplexy after COVID-19 infection, suggesting autoimmune involvement.

Key Points

  • The report aims to describe a case of narcolepsy type I developing post-COVID-19 infection.
  • Detailed clinical presentation of a 42-year-old female patient.
  • Polysomnography (PSG) and multiple sleep latency test (MSLT) conducted to confirm diagnosis.
  • Cerebrospinal fluid analysis performed to assess hypocretin levels.
  • Cerebrospinal fluid hypocretin was markedly reduced (< 40 ng/L), confirming narcolepsy type I.
  • Polysomnography indicated disturbed nocturnal sleep with a high arousal index and sleep apnea.
  • Medical treatment with methylphenidate and venlafaxine led to substantial improvement in symptoms.

Cite This Study

Merinder et al. (2026) studied this question.

synapsesocial.com/papers/6a1bd0525783ba022b6fc24ahttps://doi.org/10.1111/jsr.70372
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