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March 1, 1957Circulation Research29 citationsOpen Access

Transmembranal Potentials from the Human Heart

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JWJ. Walter WoodburyJLJohn K. LeeABAllan J. Brady

Structured PICO

P
Population
Human ventricular muscle
I
Intervention
Intracellular action potential recording using a flexibly mounted ultramicroelectrode
C
Comparator
Action potentials previously recorded from lower animals
O
Outcome
Intracellular action potentials (size, duration, and shape) correlated with lead I electrocardiogramsurrogate

Early basic electrophysiology recordings demonstrate that human ventricular intracellular action potentials are morphologically similar to those of lower animals.

Abstract

Intracellular action potentials from human ventricular muscle have been recorded with the flexibly mounted ultramicroelectrode. The complete record, correlated with the lead I electrocardiogram, is presented. The size, duration and shape of the human potentials closely resemble those previously recorded from lower animals.

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Cite This Study

Woodbury et al. (1957) studied this question.

synapsesocial.com/papers/6a1cbf450f544c23831d9db4https://doi.org/10.1161/01.res.5.2.179
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Membrane Resting and Action Potentials of Single Cardiac Muscle Fibers1950 · 75 citations
  2. 2Transmembrane Potentials of the Normal and Hypothermic Human Heart1959 · 23 citations
  3. 3A Method for Intracardiac Recording of Monophasic Action Potentials in the Dog Heart in Situ1966 · 15 citations
  4. 4Intracardiac and Intravascular Potentials Resulting from Electrical Activity of the Normal Human Heart1950 · 107 citations
  5. 5Excitation and Impulse Conduction in the Human Fetal Heart1970 · 29 citations