Are there sex-related differences in the association between coffee/caffeine consumption and atrial fibrillation?
There is a significant gap in the literature regarding sex-specific differences in the relationship between caffeine consumption and atrial fibrillation risk.
This literature review aims to explore the data of articles published on the association between coffee, caffeine and atrial fibrillation and to analyze any differences between the two sexes. Several factors influence this complex relationship; genetic, environmental and psychosocial factors come into play in the pathophysiology of atrial fibrillation. These factors are expressed differently in women and men. However, the analysis of the literature has shown that comparison works between the two sexes are extremely rare. Most population-based and prospective studies either analyze aggregated data or focus on exclusively male or female populations. This results in a lack of information that could be useful in the prevention of and treatment approach to atrial fibrillation. It is necessary to deepen this issue with dedicated studies.
Coppi et al. (Tue,) studied this question.