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Weigert (1880) was among the first to recognize infarction of the myocardium and to compare it with similar changes in other organs, for although in 1874 Hilton Fagge had described a series of cases of " fibroid disease " of the heart, which were probably myocardial infarcts, he considered them to be due to syphilis. Despite these .obseryations it was not until some thirty years later that the condition began to attract the attention of clinicians. Herrick (1912) described the clinical features and Pardee (1920) discussed the electrocardiographic changes associated with its occurrence.
Lowe et al. (Sat,) studied this question.