This paper presents the hypothesis that integrating decellularized plant leaf vascular scaffolds with organ organoids can structurally resolve the vascularization problem common to heart, liver, brain, and kidney organoid research. No prior literature combining plant leaf scaffolds with multiple organ organoids as a unified approach has been identified. This paper calls upon researchers in each field to initiate data exchange and integrated experiments.
Akihiro Watanabe (Sun,) studied this question.