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The eternal or ultimate goal of medicinal chemistry is to find most effective ways to treat various diseases and extend human beings’ life as long as possible. Human being is a biological entity. To realize such an ultimate goal, the inputs or breakthroughs from the advances in biological science are no doubt most important that may even drive medicinal science into a revolution. In this review article, we are to address this from several different angles. Keywords: Biomacromolecules, Low-frequency internal motions, Viroporin, Oligomerizes, Transmembrane, Encephalomyopathy, PseAAC/PseKNC, Web-server.
Kuo‐Chen Chou (Wed,) studied this question.