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October 11, 2023Journal of Personalized Medicine2 citationsOpen Access

Effect of Pharmaceutical Intervention in Pharmacologically Treated Hypertensive Patients—A Cluster-Randomized Clinical Trial: AFPRES-CLM Study

RMRaúl Luque del MoralMGMiguel Ángel GastelurrutiaFMFernando Martínez Martínez

Structured PICO

Does a community pharmaceutical intervention improve blood pressure control in pharmacologically treated hypertensive patients?

P
Population
347 pharmacologically treated hypertensive patients from 63 community pharmacies
I
Intervention
Community pharmaceutical intervention based on a protocol addressing individual needs for blood pressure control, including Health Education, Pharmacotherapy Follow-up, and 24 h Ambulatory Blood Pressure Measurement for 6 months
C
Comparator
Usual care in the community pharmacy
O
Outcome
Control of blood pressuresurrogate

A community pharmacy-based intervention significantly improves blood pressure control in pharmacologically treated hypertensive patients.

Abstract

BACKGROUND: Evaluate the effect of a community pharmaceutical intervention on the control of blood pressure in hypertensive patients treated pharmacologically. METHODS: A cluster-randomized clinical trial of 6 months was carried out. It was conducted in the Autonomous Community of Castilla-La Mancha (Spain). Sixty-three community pharmacies and 347 patients completed the study. Intervention patients received the community pharmaceutical intervention based on a protocol that addresses the individual needs of each patient related to the control of their blood pressure, which included Health Education, Pharmacotherapy Follow-up and 24 h Ambulatory Blood Pressure Measurement. Control patients received usual care in the community pharmacy. RESULTS: = 0.002) and improvement trends in the physical components of quality of life, measured by SF-36 questionnaire, after 6 months of pharmaceutical intervention. No significant changes were observed for any of these variables in the control group. There were also detected 354 negative medication-related outcomes that were satisfactorily resolved in a 74.9% of the cases and 330 healthcare education interventions and 29 Ambulatory Blood Pressure Monitorings were performed in order to increase adherence to pharmacological treatment and minimize Negative Outcomes associated with Medication and prevent medication-related problems. CONCLUSIONS: Community pharmaceutical intervention can increase hypertensive patients with controlled blood pressure, after 6 months, compared with usual care.

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Cite This Study

Moral et al. (2023) studied this question.

synapsesocial.com/papers/6a1e7afc5a76b87e09953cc4https://doi.org/10.3390/jpm13101484
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