Acute increases in blood pressure, heart rate, and systemic vascular resistance were associated with higher pulse wave velocity, while increases in stroke volume were associated with decreased PWV.
Observational (n=25)
How do acute hemodynamic changes affect pulse wave velocity in cardiothoracic surgical patients?
Acute hemodynamic changes, specifically increases in blood pressure, heart rate, and systemic vascular resistance, are associated with increased pulse wave velocity in cardiothoracic surgical patients.
The effect of blood pressure on pulse wave velocity (PWV) is well established. However, PWV variability with acute hemodynamic changes has not been examined in the clinical setting. The aim of the present study is to investigate the effect of hemodynamic changes on PWV in patients who undergo cardiothoracic surgery. Using data from 25 patients, we determined blood pressure (BP), heart rate (HR), and the left ventricular outflow tract (LVOT) velocity-time integral. By superimposing the radial arterial waveform on the continuous wave Doppler waveform of the LVOT, obtained by transesophageal echo, we were able to determine pulse transit time and to calculate PWV, stroke volume (SV), cardiac output (CO), and systemic vascular resistance (SVR). Increases in BP, HR, and SVR were associated with higher values for PWV. In contrast increases in SV were associated with decreases in PWV. Changes in CO were not significantly associated with PWV.
Obata et al. (Fri,) conducted a observational in Cardiothoracic surgery (n=25). Acute hemodynamic changes was evaluated on Pulse wave velocity (PWV). Acute increases in blood pressure, heart rate, and systemic vascular resistance were associated with higher pulse wave velocity, while increases in stroke volume were associated with decreased PWV.