24-hour ambulatory systolic blood pressure monitoring was more reproducible (r=0.74) than home monitoring (r=0.56) over 2 months in patients with chronic kidney disease.
Observational (n=21)
Is 24-hour ambulatory blood pressure monitoring more reproducible than home blood pressure monitoring in patients with chronic kidney disease?
In patients with CKD, 24-hour and daytime ambulatory systolic blood pressure measurements demonstrate superior reproducibility compared to 1-week averaged home measurements over a 2-month period.
Objective: The reproducibility of blood pressure (BP) measurement is important for the accurate diagnosis and management of hypertension. In this pilot study, we aimed to assess the reproducibility of home and ambulatory BP measurements in patients with chronic kidney disease (CKD). Design and method: Patients with CKD referred for the evaluation of hypertension were included in this prospective diagnostic-test study. The assessment of hypertension was performed with 2 methods: (i) 24-hour ambulatory BP monitoring (ABPM) (20-min intervals; Microlife WatchBP O3 device) and (ii) home BP monitoring (HBPM) (duplicate morning and evening BP measurements for 7 days; Microlife WatchBP Home N). These measurements were performed at baseline and were repeated over a follow-up period of 2 months. Results: The study included 21 patients (16 males, 76.2%) with a mean age of 63.0±12.1 years and a median serum creatinine of 1.6 mg/dl. The correlation coefficients between test and re-test measurements were higher for 24-hour ambulatory (r=0.74) and daytime ambulatory systolic BP (SBP) (r=0.74) than for home SBP (r= 0.56) or nighttime ambulatory SBP (r=0.63). Similarly, the reproducibility of 24-hour and daytime ambulatory SBP standard deviation of the difference (SDD): 8.9 mmHg and 9.2 mmHg, respectively was superior to that of home SBP (SDD: 10.0 mmHg) and nighttime ambulatory SBP (SDD: 11.8 mmHg). Conclusions: These preliminary data suggest that among patients with CKD, 24-hour and daytime ambulatory SBP is more reproducible than 1-week averaged home SBP and nighttime ambulatory SBP over a period of 2 months between test and re-test measurements. Larger studies are needed to confirm or refute these initial observations.
Kontogiorgos et al. (Fri,) conducted a observational in Chronic kidney disease with hypertension (n=21). 24-hour ambulatory blood pressure monitoring vs. Home blood pressure monitoring was evaluated on Reproducibility of blood pressure measurements (correlation coefficients and standard deviation of the difference). 24-hour ambulatory systolic blood pressure monitoring was more reproducible (r=0.74) than home monitoring (r=0.56) over 2 months in patients with chronic kidney disease.