Does l-norepinephrine alter renal and systemic hemodynamics in normotensive and hypertensive subjects?
The study evaluates the physiological effects of l-norepinephrine on renal and systemic hemodynamics in normotensive and hypertensive individuals.
Effect of l-norepinephrine on renal and systemic hemodynamics in normotensive and hypertensive subjects on regular salt intake * Subjectt l-Norepineph-Urine Age rine volume GFR RPF FF RR Pm Pulse yrs Aglminl ml/min ml/min ml/min % dynesmm Hg rate/min 1.73 m2 sec-cm' Normotensive subjects M.S. Control 39 4.9 13.2 21.4 42.4 O.V. Control 35 2.6 6.6 12.3 20.0
Gombos et al. (1962) studied this question.