Doppler echocardiography-derived mitral regurgitant fraction correlated well (r = 0.82) with regurgitant grades determined by left ventriculography.
Observational (n=50)
Does Doppler echocardiography reliably measure mitral regurgitation compared to left ventriculography in patients with and without valvar heart disease?
Doppler echocardiography provides a reliable, non-invasive method for measuring mitral regurgitation that correlates well with invasive left ventriculography.
Effect estimate: r = 0.82
In an attempt to develop a new approach to the non-invasive measurement of mitral regurgitation, Doppler echocardiography and left ventriculography were performed in 20 patients without valvar heart disease (group A) and in 30 patients with pure mitral regurgitation (group B). Volumetric flows through the aortic and the mitral orifices were determined by Doppler echocardiography. Aortic flow (AF) was calculated as the product of the aortic orifice area and the systolic velocity integral. The mitral flow (MF) was calculated as the product of the corrected mitral orifice area and the diastolic velocity integral. The mitral regurgitant fraction (RF) was calculated as RF = 1 - AF/MF. In group A aortic and mitral flow were very similar and the difference between the two did not differ significantly from zero. In group B the mitral flow was significantly larger than the aortic flow. There was a good correlation (r = 0.82) between the regurgitant fraction determined by Doppler echocardiography and the regurgitant grades determined by left ventriculography. The regurgitant fraction increased significantly with each grade of severity. These results show that Doppler echocardiography can be used to give a reliable measure of both aortic and mitral flow. This technique is a new and promising approach to the non-invasive measurement of mitral regurgitation.
Zhang et al. (1985) conducted an observational in Mitral regurgitation (n=50). Doppler echocardiography vs. Left ventriculography was evaluated on Correlation between regurgitant fraction by Doppler echocardiography and regurgitant grades by left ventriculography (r = 0.82). Doppler echocardiography-derived mitral regurgitant fraction correlated well (r = 0.82) with regurgitant grades determined by left ventriculography.