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Abstract The subcellular distribution of the A and B proteins of lactose synthetase (EC 2.4.1.c) has been determined in bovine and rat mammary tissue. The A protein is mainly associated with the microsomal fraction, whereas the B protein is distributed between the microsomal and soluble fraction. The B protein is more readily dissociated from the microsomes than the A protein. Microsomes present in milk have the same specific activity of the A and B protein as microsomes isolated from mammary tissue.
Brodbeck et al. (Thu,) studied this question.
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