Why the study?
Does antithrombotic therapy reduce major cardiovascular events in patients with hypertension?
Population
Patients with hypertension
Design
Review
Key result
In hypertensive patients, adding aspirin to antihypertensive treatment reduces major cardiovascular events by 15%, though bleeding risks may outweigh benefits in low-risk individuals.
Authors
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Supports cautious aspirin use in select high-risk hypertensives; leaves open need for updated RCTs on net benefit.
Does antithrombotic therapy reduce major cardiovascular events in patients with hypertension?
Aspirin 75 mg daily is recommended for secondary and primary prevention in specific high-risk hypertensive patients, though bleeding risks must be weighed in low-risk individuals.
Lip et al. (2001) conducted a review in Hypertension. Antithrombotic therapy (aspirin) was evaluated. In hypertensive patients, adding aspirin to antihypertensive treatment reduces major cardiovascular events by 15%, though bleeding risks may outweigh benefits in low-risk individuals.