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Application of the twelve principles of green chemistry can deliver higher efficiency and reduce the environmental burden during chemical synthesis. As a result of recent advances in genomics, proteomics and pathway engineering, biocatalysis is emerging as one of the greenest technologies. Enzymes are highly efficient with excellent regioselectivity and stereoselectivity. By conducting reactions in water under ambient reaction conditions, both the use of organic solvents and energy input are minimized.
Ran et al. (Tue,) studied this question.