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In an earlier paper in this symposium Mirsky has described how interphase chromosomes of many organs can be isolated in quantities sufficient for analysis by macrochemical methods; and he has summarized the results of study of the nucleic acids and proteins that make up the bulk of the constituents of these chromosomes. These analyses have shown clearly that there is a uniform pattern of chromosome composition, for the same four fractions are found in every case, namely: an abundance of desoxypentose nucleic acid, along with some pentose nucleic acid, and two clearly separable protein fractions, histone and residual protein.
Pollister et al. (Wed,) studied this question.