Velocity-encoded MRI successfully estimated mean aortic pulse pressure at 54.2 +/- 16.4 mmHg and pulse wave velocity at 5.03-5.37 m/s in healthy young adults.
Cross-Sectional (n=11)
Does velocity-encoded MRI allow for noninvasive assessment of aortic pulse pressure and pulse wave velocity in healthy young adults?
Velocity-encoded MRI is a feasible noninvasive method for determining aortic pulse pressure and pulse wave velocity in young adults.
PURPOSE: To investigate the feasibility of assessing, noninvasively, aortic pulse pressure (APP) and pulse wave velocity (PWV) in the ascending aorta of young adults by means of velocity-encoded magnetic resonance (MR) imaging. MATERIALS AND METHODS: In a series of 11 healthy volunteers, velocity-encoded MR imaging provided pairs of magnitude and phase-contrast images. Blood flow velocity and aortic cross-sectional area (CSA) were determined with a 30-msec temporal resolution. A model analysis revealed that variation in aortic CSA and in maximal blood flow velocity throughout systole could be used to estimate APP and, hence, to derive PWV by means of two different methods. RESULTS: Mean +/- SD values of the APP for the series were 54.2 +/- 16.4 mmHg (range 32.2-84.1 mmHg). The ascending aortic PWV mean +/- SD values were 5.03 +/- 1.10 m/second and 5.37 +/- 1.23 m/second according to the two methods, and both estimates were not significantly different (95% confidence level). CONCLUSION: These results are in agreement with previously published data, suggesting that APP and PWV can be determined, noninvasively, in young adults using MRI.
Laffon et al. (2004) conducted a cross-sectional in Healthy (n=11). Velocity-encoded magnetic resonance (MR) imaging was evaluated on Aortic pulse pressure (APP) and pulse wave velocity (PWV). Velocity-encoded MRI successfully estimated mean aortic pulse pressure at 54.2 +/- 16.4 mmHg and pulse wave velocity at 5.03-5.37 m/s in healthy young adults.