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August 1, 2005American Journal of Hypertension72 citationsOpen Access

Association of Risk Factors With Increased Pulse Wave Velocity Detected by a Novel Method Using Dual-Channel Photoplethysmography

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WTW TSAIJCJ CHENMWMin‐Hong Wang

Key Result

Pulse wave velocity measured by a novel dual-channel photoplethysmography method was significantly correlated with the standard applanation tonometry method (r = 0.678, P < .01).

Study Design

Type

Cross-Sectional (n=100)

Structured PICO

Does dual-channel photoplethysmography accurately measure pulse wave velocity compared to standard applanation tonometry in asymptomatic subjects?

P
Population
100 asymptomatic adults (54 men, 46 women) aged 19 to 64 years.
E
Exposure
Dual-channel photoplethysmography (PWV-DVP) for measuring pulse wave velocity
C
Comparator
Standard method using applanation tonometry (PWV-AT)
O
Outcome
Correlation between PWV measured by dual-channel PPG and applanation tonometrysurrogate

A novel dual-channel photoplethysmography method for measuring pulse wave velocity correlates well with standard applanation tonometry, offering a potential new tool for assessing arterial stiffness.

Main Result

Effect estimate: r = 0.678

p-value: p=< .01

Abstract

BACKGROUND: Pulse wave velocity (PWV) is correlated with cardiovascular risk. This study presents a new method for measuring the arterial PWV by simultaneously recording the digital volume pulse through the finger and the toe by way of dual-channel photoplethysmography (PPG). METHODS: In this study, 100 asymptomatic subjects (54 men and 46 women, 19 to 64 years of age) were enrolled. The PWV was measured both by dual-channel PPG (PWV-DVP) and by the standard method that current used applanation tonometry (PWV-AT). The developed dual-channel PPG system recorded digital volume pulse simultaneously from both the finger and toe. Time of pulse transition was measured on the time delay difference between two digital volume pulses. The PWV was calculated by dividing the distance between finger and toe by that of transit time. RESULTS: The PWV-DVP was significantly correlated with PWV-AT (r = 0.678, P < .01). With multivariate analysis controlled for age, heart rate, systolic blood pressure, and diastolic blood pressure, PWV-DVP was still significantly correlated with PWV-AT (r = 0.669, P < .01). Subjects with hypertension and dyslipidemia had significant higher PWV detected by both methods. CONCLUSION: This study showed that PWV measured with dual-channel PPG system correlated very well with that measured using the traditional method.

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Cite This Study

TSAI et al. (2005) conducted a cross-sectional in Asymptomatic (n=100). Dual-channel photoplethysmography (PWV-DVP) vs. Applanation tonometry (PWV-AT) was evaluated on Correlation between PWV measured by dual-channel PPG and applanation tonometry (r = 0.678, p=< .01). Pulse wave velocity measured by a novel dual-channel photoplethysmography method was significantly correlated with the standard applanation tonometry method (r = 0.678, P < .01).

synapsesocial.com/papers/6a219277582b7ad9ebabd273https://doi.org/10.1016/j.amjhyper.2005.03.739
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