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August 1, 1996Clinical Science121 citations

Finger Arterial versus Intrabrachial Pressure and Continuous Cardiac output during Head-up Tilt Testing in Healthy Subjects

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WJWilbert T. JellemaSt. Antonius ZiekenhuisBIBen P.M. ImholzErasmus MCJGJeroen van GoudoeverAmsterdam UMC Location University of Amsterdam

Key Result

Continuous non-invasive Finapres recordings closely followed intrabrachial values during a 30-minute head-up tilt, with a stroke volume difference of 0.3 ± 5%.

Key Points

  • This research aims to determine if finger arterial pressure can replace intrabrachial pressure during head-up tilt tests and the reliability of stroke volume assessment via pulse contour analysis.
  • Eight healthy subjects underwent a 30 min head-up tilt at 70 degrees with simultaneous measurements of finger arterial and intrabrachial pressures.
  • Continuous stroke volume changes were computed using a pulse contour algorithm from both finger and brachial pressure waveforms.
  • Accuracy and precision of measurements were evaluated based on group-averaged differences in blood pressure readings.
  • The average difference in mean blood pressure between FINAP and IAP increased by 7 mmHg during the head-up tilt (P < 0.001).
  • Stroke volume difference between FINAP and IAP was 0.3 +/- 5% (mean +/- SD), consistent regardless of tilt duration (P > 0.05).
  • Finapres monitoring can effectively track rapid blood pressure changes in clinical settings during prolonged head-up tilting.

Study Design

Type

Observational (n=8)

Structured PICO

Does continuous non-invasive finger arterial pressure measurement accurately reflect intrabrachial pressure and cardiac output during head-up tilt testing in healthy subjects?

P
Population
8 healthy subjects undergoing a 30-minute 70-degree passive head-up tilt test.
E
Exposure
Continuous, non-invasive finger arterial pressure (Finapres) recordings
C
Comparator
Intrabrachial pressure (IAP) measurements
O
Outcome
Accuracy (group-averaged FINAP-IAP difference) and precision (SD of the difference) of blood pressure measurementssurrogate

Continuous non-invasive finger arterial pressure monitoring provides reliable tracking of blood pressure and relative stroke volume changes during head-up tilt testing compared to invasive intrabrachial measurements.

Main Result

Effect estimate: SBP difference 4 ± 9 mmHg; MBP difference -5 ± 9 mmHg; DBP difference -5 ± 9 mmHg

Abstract

The aims of this study were to determine the clinical feasibility of continuous, non-invasive Finapres recordings as a replacement for intrabrachial pressure during a 30 min head-up tilt, and the reliability of continuous cardiac output computation by pulse contour analysis from the finger arterial versus the brachial waveform. 2. In eight healthy subjects a 30 min 70 degrees passive head-up tilt was performed. Finger arterial (FINAP) and intrabrachial (IAP) pressures were measured simultaneously. Beat-to-beat changes in stroke volume were computed using a pulse contour algorithm. 3. Accuracy (the group-averaged FINAP-IAP difference) and precision (the SD of the difference) of Finapres measurements were 4 and 9 mmHg for systolic blood pressure, -5 and 9 mmHg for mean blood pressure and -5 and 9mmHg for diastolic blood pressure. 4. The time course of the FINAP-IAP differences during head-up tilt showed a linear trend (P 0.05). This difference did not change at low blood pressure levels (0.5 +/- 6%). 5. The qualitative performance of the Finapres allows it to be used in the clinical setting as a monitor of sudden changes in blood pressure induced by a 30 min head-up tilt. Relative changes in stroke volume, as obtained by pulse contour analysis of the finger arterial waveform, closely follow intrabrachial values during long-duration head-up tilt and associated arterial hypotension.

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Cite This Study

Jellema et al. (1996) conducted an observational in Healthy subjects (n=8). Continuous non-invasive Finapres recordings (finger arterial pressure) vs. Intrabrachial pressure (IAP) was evaluated on Accuracy and precision of Finapres measurements for blood pressure and stroke volume compared to intrabrachial pressure (SBP difference 4 ± 9 mmHg; MBP difference -5 ± 9 mmHg; DBP difference -5 ± 9 mmHg). Continuous non-invasive Finapres recordings closely followed intrabrachial values during a 30-minute head-up tilt, with a stroke volume difference of 0.3 ± 5%.

synapsesocial.com/papers/6a21950ebd959c3a83abe782https://doi.org/10.1042/cs0910193
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