What is the clinical evidence from this study?

Study design: Observational. Population: Cardiovascular responses to stress (n=171). Intervention: Type A behavior, potential for hostility, and parental history of hypertension vs. Adolescents without these traits or parental history. Primary outcome: Cardiovascular responses (systolic and diastolic blood pressure) to three behavioral stressors.

September 1, 1988

Influences of Potential for Hostility, Type A Behavior, and Parental History of Hypertension on Adolescents’ Cardiovascular Responses During Stress

Key Result

Adolescents with a hypertensive parent, Type A behavior, or high potential for hostility exhibited elevated systolic and diastolic blood pressure responses to behavioral stressors.

Study Design

Type

Observational (n=171)

Structured PICO

Do Type A behavior, potential for hostility, and parental history of hypertension influence adolescents' cardiovascular responses to behavioral stressors?

Population

171 male and female adolescents in grades 6 to 12 assessed for cardiovascular responses to behavioral stressors.

Exposure

Assessment of Type A behavior, potential for hostility, and parental history of diagnosed hypertension during exposure to three behavioral stressors.

Comparator

Adolescents without hypertensive parents, or with lower hostility/Type B behavior.

Outcome

Cardiovascular responses (systolic and diastolic blood pressure) to three behavioral stressors.surrogate

Early signs of hostility and parental history of hypertension are associated with exaggerated cardiovascular responses to stress in adolescents, suggesting a potential pathophysiological mechanism for future cardiovascular disease.

Abstract

ABSTRACT We investigated the influences of Type A behavior, potential for hostility, and parental history of diagnosed hypertension on adolescents’ cardiovascular responses to three behavioral stressors. The participants were 72 male and 99 female adolescents enrolled in grades 6 to 12. Results showed that adolescents with a hypertensive parent had larger diastolic blood pressure responses during all three stressors than did adolescents without hypertensive parents; this effect was particularly pronounced among the Type As. Adolescents rated as high on potential for hostility had elevated systolic and diastolic blood pressure responses, particularly during isometric exercise. Results regarding parental history of hypertension and Type A replicate previous studies in adolescents. Results regarding potential for hostility showed for the first time that early signs of hostility are related to psychophysiological responses thought to be pathophysiological mechanisms in the etiology of cardiovascular diseases.

AI से पूछें

Bookmark