The Physiology and Pathology of Exposure to Stress: A Treatise Based on the Concepts of the General-Adaptation-Syndrome and the Diseases of Adaptation

The author has played a primary role in the development of the theory with which this impressive volume deals. In this carefully developed treatise, the principal facts and theories on which the general adaptation syndrome concept is based are thoroughly discussed. Definitions of terminology used are outlined, and the various alarming stimuli or factors which elicit the syndrome are described. Whether one agrees with the concept of the syndrome or not, work with pituitary adrenocorticotropic hormone (ACTH) and cortisone has lent support to many of the basic concepts on which its theory depends. If future events prove that this concept is correct, it will prove to be one of the significant medical advances in understanding the nature of disease of this century. One can carp at the somewhat rigid division of the adrenal steroids into mineralocorticoids, glucocorticoids, medulloids, lipocorticoids and others, since many of the steroids have been shown to