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January 1, 2003Chemical and Pharmaceutical Bulletin40 citationsOpen Access

A New Stilbene with Tyrosinase Inhibitory Activity from Chlorophora excelsa.

KSKuniyoshi ShimizuSYSeiji YasutakeRKRyuichiro Kondo

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Abstract

A new stilbene, 4-(2"E)-7"-hydroxy-3",7"-dimethyloct-2"-enyl-2',3,4',5-tetrahydroxy-trans-stilbene (1), and the known compound chlorophorin (2) were isolated from the heartwood of Chlorophora excelsa. Both 1 and 2 showed tyrosinase inhibitory activity with IC(50) values of 96 and 1.3 microM, respectively.

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Shimizu et al. (2003) studied this question.

synapsesocial.com/papers/6a263d08e211116b86fa3552https://doi.org/10.1248/cpb.51.318
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