Abstract Context: Breast cancer (BC) in young women represents a unique clinical challenge, and its incidence is increasing. Aims: Evaluate and compare the clinical, pathological, and treatment characteristics of BC in women under 50 years old. Settings and Design: A retrospective study was conducted on patients diagnosed with BC under the age of 50. Subjects and Methods: Clinical, demographic, pathological, and treatment-related data were collected and analyzed, with patients divided into two age groups (≤40 vs. 41–49 years). Statistical Analysis Used: Descriptive and comparative analyses were performed using SPSS ® . Results: BC risk factors that had statistically significant differences between the groups were body max index, number of gestations/parity, alcohol consumption, and previous breast disease. Younger women showed more aggressive tumors and were more frequently diagnosed with genetic mutations. Recurrence was also slightly higher in this group (11.4% vs. 9.8%), but without statistical significance. Conclusions: Young women with BC tend to present with more aggressive tumors and higher stage at diagnosis, posing specific challenges related to treatment choice and lifelong support.
Silva et al. (2026) studied this question.