Background: Modern pathology explains disease through cellular injury, inflammation, immune dysregulation, molecular abnormalities, and genetic mechanisms. In contrast, the Organon of Medicine emphasises symptom totality, individual susceptibility, and constitutional assessment. Integrating these perspectives may strengthen evidence-informed homoeopathic practice. Objective: To critically evaluate the relationship between modern pathology and organ-based individualised therapeutic decision-making. Methods: A narrative review of pathology literature, homoeopathic philosophy, and contemporary concepts of clinicopathological correlation was undertaken. Results: Pathological investigations provide diagnostic precision and prognostic information, whereas Organon principles guide individualised therapeutic choices through constitutional assessment and symptom analysis. Conclusion: Modern pathology and Organon of Medicine contribute complementary dimensions to patient-centred healthcare and may support interdisciplinary clinical practice.
Desale et al. (Mon,) studied this question.