Simultaneous recordings of skin microvascular blood flow and oxygen saturation in healthy subjects demonstrated significant wavelet phase coherence at cardiac frequencies and between 0.01-0.1 Hz.
Cross-Sectional (n=88)
The study demonstrates causal connections between skin blood flow and oxygen saturation within specific frequency ranges, providing new insights into blood oxygenation dynamics.
We have determined the wavelet phase coherence between simultaneously recorded microvascular blood flow and oxygen saturation signals from 88 healthy subjects, thus enabling us to study their common fluctuations. Measurements were taken for 30 min from the arm and leg, at two depths. In the skin, blood flow and oxygen saturation were found to be coherent both at the cardiac frequency and below 0.1 Hz down to about 0.01 Hz. Coherence in the arm extends to lower frequencies than that in the leg. From the deeper recordings, no coherence was found on either limb. The existence of coherence between skin blood flow and oxygen saturation demonstrates causal connections between them within certain frequency ranges. The method has yielded the first detailed insight into the dynamics of blood oxygenation.
Bernjak et al. (Thu,) conducted a cross-sectional in Healthy subjects (n=88). Simultaneous measurement of microvascular blood flow and oxygen saturation was evaluated on Wavelet phase coherence between blood flow and oxygen saturation. Simultaneous recordings of skin microvascular blood flow and oxygen saturation in healthy subjects demonstrated significant wavelet phase coherence at cardiac frequencies and between 0.01-0.1 Hz.
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