The rise of multidrug-resistant (MDR) bacteria poses a significant global health threat, prompting the search for novel antimicrobial agents to combat these infections. Silica-coated silver nanoparticles (SiO₂@AgNPs) have shown promise due to their potent antibacterial properties, enhanced stability, biocompatibility, and controlled silver ion release. These nanoparticles are efficient in combating a variety of pathogens, including MDR bacteria and biofilm-forming microbes. This review examines the synthesis methods, antibacterial mechanisms, and potential applications of SiO₂@AgNPs, including their use in drug delivery systems, wound dressing, and antimicrobial coatings. Despite their advantages, concerns regarding their cytotoxicity and environmental impact remain, emphasizing the need for ongoing research and regulatory oversight. As research advances, SiO₂@AgNPs hold significant potential for combating resistant infections and improving patient care in the future.
S et al. (Sat,) studied this question.