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February 1, 1998Antimicrobial Agents and Chemotherapy59 citationsOpen Access

Characterization of FOX-3, an AmpC-Type Plasmid-Mediated β-Lactamase from an Italian Isolate of Klebsiella oxytoca

AMAnna MarcheseGAGuillaume ArletGSGian Carlo Schito

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Abstract

Klebsiella oxytoca 1731, which showed a wide spectrum of resistance to beta-lactams, including cefoxitin, was isolated in 1994 from a patient in Genoa, Italy. This strain contained a plasmid-mediated AmpC beta-lactamase with a pI of 7.25. Sequencing of the corresponding DNA of K. oxytoca 1731 revealed 96 and 97% identities of the deduced amino acid sequence with FOX-1 and FOX-2, respectively.

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Marchese et al. (1998) studied this question.

synapsesocial.com/papers/6a62e373f2b26b06470944behttps://doi.org/10.1128/aac.42.2.464
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