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December 19, 2006American Journal of Roentgenology118 citations

Primary Pulmonary Hypertension: 3D Dynamic Perfusion MRI for Quantitative Analysis of Regional Pulmonary Perfusion

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YOYoshiharu OhnoHHHiroto HatabuKMKenya Murase

Key Result

Three-dimensional dynamic contrast-enhanced MRI has potential for the assessment of disease severity as indicated by PVR and MPAP in patients with primary pulmonary hypertension.

Study Design

Type

Observational

Structured PICO

Does 3D dynamic contrast-enhanced MR perfusion accurately assess disease severity (PVR and MPAP) in patients with primary pulmonary hypertension?

P
Population
Patients with primary pulmonary hypertension (PPH)
E
Exposure
3D dynamic contrast-enhanced MR perfusion
O
Outcome
Assessment of disease severity as indicated by pulmonary vascular resistance (PVR) and mean pulmonary artery pressure (MPAP)surrogate

3D dynamic contrast-enhanced MRI may be a useful non-invasive tool to assess disease severity (PVR and MPAP) in patients with primary pulmonary hypertension.

Abstract

OBJECTIVE: The purpose of this study was to determine whether quantitative pulmonary perfusion parameters obtained from 3D dynamic contrast-enhanced MR perfusion data can be used to assess the severity of primary pulmonary hypertension (PPH) as indicated by pulmonary vascular resistance (PVR) and mean pulmonary artery pressure (MPAP). CONCLUSION: Three-dimensional dynamic contrast-enhanced MRI has potential for assessment of disease severity as indicated by PVR and MPAP in patients with PPH.

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Cite This Study

Ohno et al. (2006) conducted an observational in Primary pulmonary hypertension (PPH). 3D dynamic contrast-enhanced MR perfusion was evaluated on Disease severity as indicated by pulmonary vascular resistance (PVR) and mean pulmonary artery pressure (MPAP). Three-dimensional dynamic contrast-enhanced MRI has potential for the assessment of disease severity as indicated by PVR and MPAP in patients with primary pulmonary hypertension.

synapsesocial.com/papers/6a6c8d9a31a3df824326bd1ehttps://doi.org/10.2214/ajr.05.0135
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