Pulsed Doppler ultrasound detected mitral regurgitation with 94% sensitivity, 90% specificity, and predictive values of 90% (positive) and 93% (negative).
Cross-Sectional (n=64)
Does pulsed Doppler ultrasound accurately detect mitral regurgitation compared to left ventricular angiography in patients with various heart diseases?
Pulsed Doppler ultrasound demonstrates high sensitivity (94%) and specificity (90%) for the non-invasive detection of mitral regurgitation compared to left ventricular angiography.
Effect estimate: Sensitivity 94%, specificity 90%
Sixty-four patients with various heart diseases were evaluated for mitral regurgitation (MR) by left ventricular angiography and pulsed Doppler ultrasound within 2-3 days. Adequate Doppler recordings were obtained from 60 patients. The sensitivity of Doppler in detecting MR was 94%, specificity 90% and predictive value for a positive and a negative Doppler examination 90 and 93%, respectively. Two of the 3 false positive Doppler recordings were from patients with coronary heart disease, ischemic papillary muscle dysfunction may have caused MR inconsistently. Two false negative Doppler recordings may be related to problems in placing the ultrasonic sample volume at the systolic retrograde blood stream in the left atrial cavity. It is concluded that pulsed Doppler ultrasound, being a transcutaneous, non-invasive method, is a valuable tool in detecting MR. So far, we have not been able to quantitate the regurgitation.
Knutsen et al. (1981) conducted a cross-sectional in Mitral regurgitation (n=64). Pulsed Doppler ultrasound vs. Left ventricular angiography was evaluated on Detection of mitral regurgitation (Sensitivity 94%, specificity 90%). Pulsed Doppler ultrasound detected mitral regurgitation with 94% sensitivity, 90% specificity, and predictive values of 90% (positive) and 93% (negative).