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August 24, 2022Perioperative Medicine2 citationsOpen Access

Frailty in the over 65’s undergoing elective surgery (FIT-65) – a three-day study examining the prevalence of frailty in patients presenting for elective surgery

DHDavid A. HarvieFWFrances WensleyLMLewis Matthews

Key Result

In patients aged 65 years or older undergoing elective surgery, the prevalence of frailty was 17.0%, and frail patients were more likely to present with modifiable pre-operative co-morbidities.

Study Design

Type

Cross-Sectional (n=218)

Blinding

Single-blind

Multicenter

Yes

Structured PICO

P
Population
218 adults aged 65 years or older undergoing elective surgery across eight UK hospitals, assessed for frailty and followed for 30 days.
E
Exposure
Pre-operative frailty screening using the Reported Edmonton Frail Scale (REFS)
O
Outcome
Prevalence of frailty in patients aged over 65 years undergoing elective surgery

Frailty is present in 17% of patients over 65 undergoing elective surgery and is associated with modifiable comorbidities and a lower likelihood of being discharged home, supporting routine pre-operative screening.

Limitations

  • Subjective element in patient reporting of functional status using the Reported Edmonton Frail Scale.
  • Heterogeneous group of surgical specialties with potentially differing frailty rates.
  • Pre-selection bias due to the COVID-19 pandemic impacting elective surgery lists, likely selecting less vulnerable patients.
  • Exclusion of patients without capacity, potentially missing the most severely frail patients (e.g., those with advanced dementia).
  • Heterogeneous group of surgical specialties
  • Impact of COVID-19 pandemic causing pre-selection bias
  • Exclusion of patients without capacity

Abstract

BACKGROUND: Frailty increases the risk of perioperative complications, length of stay, and the need for assisted-living after discharge. As the UK population ages the number of frail patients presenting for elective surgery in the UK is likely to grow. Despite the potential benefits of early diagnosis, frailty is not uniformly screened for in UK elective surgical patients and its prevalence remains unclear. The primary aim of this study was to assess the prevalence of frailty in patients aged over 65 years undergoing elective surgery. METHODS: We performed a prospective cross-sectional observational study in eight UK hospitals. Data were collected over three consecutive days with follow-up at 30 days. HRA approval was obtained (REC 20/SC/0121) and signed informed consent obtained. Participants were eligible for inclusion if they were 65 years or older and undergoing elective surgery. Pre-operative data were collected from hospital notes by anaesthetic trainees. A member of the research team blinded to the pre-operative dataset screened each participant for frailty pre-operatively using the Reported Edmonton Frail Scale (REFS). Post-operative data were collected from the notes on day of surgery and at 30 days. Participants were defined as "frail" if they scored 8 or more on the REFS. RESULTS: Two hundred twenty eight participants were recruited during the study period of whom 218 proceeded to surgery. There were 103 females and 115 males. Median age was 75 years (interquartile range 70-80). Thirty-seven participants (17.0%) were identified as frail. Frail patients were older, had a higher ASA score, were more likely to have carers and were more likely to be anaemic or present with ECG abnormalities. There were no differences in gender, BMI, place of residence or smoking status for patients identified as frail versus non-frail. There was no difference in length-of-stay between frail and non-frail patients, although those identified as frail were less likely to be discharged to their own home. CONCLUSION: We found the prevalence of frailty in a mixed population of elective surgical patients aged 65 or over to be 17.0%. Furthermore, we found the REFS to be a practical tool for pre-operative frailty screening. Frail patients presented for elective surgery with modifiable co-morbidities which could have been optimised pre-operatively. Early screening could highlight frail patients, allowing time for pre-operative planning and evidence-based optimisations of comorbidities. We therefore encourage the adoption of frailty assessment as a routine part of pre-operative assessment.

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Cite This Study

Harvie et al. (2022) conducted a cross-sectional in Elective surgery (n=218). Frailty vs. Non-frail was evaluated on Prevalence of frailty (Reported Edmonton Frail Scale score ≥ 8). In patients aged 65 years or older undergoing elective surgery, the prevalence of frailty was 17.0%, and frail patients were more likely to present with modifiable pre-operative co-morbidities.

synapsesocial.com/papers/6a8b0e5e634d203318b1f1efhttps://doi.org/10.1186/s13741-022-00272-1
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