Garvan Institute of Medical Research

Recent papers from Garvan Institute of Medical Research

1. Genetic variants shape single-cell chromatin accessibility and disease riskNature · 2026
2. Rare and common genetic variants shape single-cell immune gene expressionNature · 2026
3. Patterns of Progression on Posttreatment Imaging During [ 177 Lu]Lu-PSMA Radiopharmaceutical TherapyJournal of Nuclear Medicine · 2026
4. Disruption of the N-terminal domain in a STAT3 hyper-IgE syndrome variant causes disease by sequestering STAT3 in the cytoplasmScience Signaling · 2026
5. An Australian Narrative Review of Adoptive Cellular Therapies in Malignancy: Expanding Indications, Referral Pathways and Safety Beyond Specialist CentresThe Medical Journal of Australia · 2026
6. Multimodal prediction of incident heart failure using clinical data, polygenic risk scores, and electrocardiogram-based artificial intelligenceEuropean Heart Journal · 2026
7. Prompt-driven large language model for evidence extraction in implementation science: exploring semantic similarity between manual and automated coding across studiesImplementation Science Communications · 2026
8. An IL-21R STAT hypomorph circumvents functional redundancy in germinal centre responseseLife · 2026
9. Disease associations for rare immune genetic variants require statistical or rule-based supportJournal of Human Immunity · 2026
10. Long‐Term Impact of Bariatric Surgery and Dietary Interventions on Weight Loss, Physical Activity, and Food PreferencesObesity · 2026
11. GCH1 p. Ser80Asn Confers Risk for Parkinson's Disease in East Asian PopulationsMovement Disorders · 2026
12. Biallelic variants in PIKFYVE cause a hypomyelinating leukodystrophy with endolysosomal dysfunctionBrain · 2026
13. Psychosocial Implications of Genome Sequencing for Inherited Cardiac Disease: Outcomes From the Australian Genomics Cardiovascular Disorders FlagshipHeart Lung and Circulation · 2026
14. Light Chain Cardiac Amyloidosis With Skeletal Muscle WeaknessJACC Case Reports · 2026
15. Genotype and arrhythmic risk in dilated cardiomyopathyEuropean Heart Journal · 2026
16. Spatial Atlas of Small Cell Lung Carcinoma Reveals Intratumoral Tumor‐State Heterogeneity and an MMP12 + Macrophage NicheCancer Science · 2026
17. Multiscale mechanical analysis of live breast cancer spheroids by micro‐compression and Brillouin imagingJournal of Microscopy · 2026
18. hpci improves reproducibility of computational biology research by integrating Continuous Integration with High Performance Computing clustersBioinformatics · 2026
19. Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast CancerAdvanced Science · 2026
20. Contemporary Chemotherapy Benchmarks for Molecularly Defined Advanced NSCLC: Reconstructed Individual Patient-Level Data of 22 Randomized TrialsLung · 2026