Deutschen Konsortium für Translationale Krebsforschung

Recent papers from Deutschen Konsortium für Translationale Krebsforschung

1. Metastatic prostate cancer with neuroendocrine differentiation and liver metastases: prognosis and response to platinum-based chemotherapyWorld Journal of Urology · 2026
2. Rapid proteasomal degradation of mutant feline McDonough sarcoma-like tyrosine kinase-3 overcomes inhibitor resistance mechanisms of acute myeloid leukemia cellsLeukemia · 2026
3. Predicting [ 90 Y]Y-FAPI-46 Tumor Absorbed Dose from Single-Time-Point [ 68 Ga]Ga-FAPI-46 PET/CT ImagingJournal of Nuclear Medicine · 2026
4. EHMT1/2-LIG1 axis enhances Temozolomide Sensitivity in Experimental GliomaNeuro-Oncology Advances · 2026
5. The preCDD Network as a Model for Academic Preclinical Cancer Drug Development in GermanyHuman Gene Therapy · 2026
6. Bone metastases identify a high-risk subgroup in metastatic neuroendocrine tumors with particular relevance in NETs of unknown primaryFrontiers in Endocrinology · 2026
7. Spatial niche organization shapes clinical heterogeneity in Ewing sarcoma2026
8. Identification and characterization of a novel distinct Pineal Neoplasm with Neuroendocrine and Epithelial Differentiation (PINNED)Acta Neuropathologica · 2026
9. TET2-driven activation of AGO2 links epigenetic remodeling to myeloid commitment and leukemiaScience Advances · 2026
10. Microbeam radiotherapy – clinical and dosimetric investigation of a first clinical applicationRadiation Oncology · 2026
11. Cytotoxic activity of selinexor in BRAFV600E-driven pediatric low-grade glioma 3D culturesActa Neuropathologica Communications · 2026
12. Combination of oral fluoropyrimidines and EGFR-directed antibodies in frail patients with metastatic colorectal cancer: a systematic reviewJournal of Cancer Research and Clinical Oncology · 2026
13. Biomarker-guided treatment strategies for patients with gliomas in clinical practiceNeuro-Oncology · 2026
14. +A CAR T cell-amplified suppressive B cell circuit in AML2026
15. Selpercatinib in Pediatric and Adolescent Patients With RET -Altered Solid Tumors: Safety and Efficacy Results From the Phase I/II LIBRETTO-121 StudyJournal of Clinical Oncology · 2026
16. The molecular heterogeneity and clinical impact of genomic driver alterations in prostate cancerNature Communications · 2026
17. Novel strategies in radiation therapy: high-dose radiotherapy for oligometastatic/oligo-progressive thymic tumorsMediastinum · 2026
18. Micronuclear ecDNA constrains tumor cell fitness and is associated with favorable patient survivalNature Genetics · 2026
19. Familial Cancers Associated With Cancers of the Breast, Prostate, Colorectum, and Lung in SwedenInternational Journal of Cancer · 2026
20. Histone neutralization protects the ischemic brain against the consequences of stroke-associated pneumoniaActa Neuropathologica · 2026