Wellcome/MRC Cambridge Stem Cell Institute

Recent papers from Wellcome/MRC Cambridge Stem Cell Institute

1. The transcription factor BCL11A restores differentiation potential to aged oligodendrocyte progenitor cellseLife · 2026
2. A new reporter strategy reveals a subset of nonmigratory hematopoietic stem cells located in a dynamic bone marrow nicheBlood · 2026
3. A muscle-enriched mitochondrial protein regulates postnatal heart growth through mitonuclear ubiquinone–PPAR signalingProceedings of the National Academy of Sciences · 2026
4. From evidence to delivery: Optimising SGLT2 inhibitor therapy in heart failureInternational Journal of Cardiology · 2026
5. Standardizing Cell Ontology terms for cross-study integration in the female reproductive tractScience Advances · 2026
6. Endogenous retrovirus control of calbindin is essential for human early embryogenesisScience Advances · 2026
7. Dynamics of human cardiogenesis and its disruption in trisomy 21Nature · 2026
8. A preinvasive regulatory T cell axis for lung cancer interceptionNature · 2026
9. PSC ‐ DM : A Validated Clinical Diagnostic Model for Distinguishing Primary From Secondary Sclerosing CholangitisLiver International · 2026
10. ArchMap is a web-based platform for reference-based analysis of single-cell datasetsNature Genetics · 2026
11. Cell atlas of the developing human meninges reveals a dura-like nature of meningiomasNature Cell Biology · 2026
12. EL-PACA: ensembled low-dimensional projections for accurate cell-type annotation using deep learning for single-cell transcriptomics of human tissues and organoidsScientific Reports · 2026
13. Tumor digital twins uncover therapeutic strategies in triple-negative breast cancerCell Reports Medicine · 2026
14. Spatially resolved multiomics of human meningeal development reveal lineage and disease dynamicsNature Cell Biology · 2026
15. Development and validation of a model for stratifying haematological malignancy risk in primary care using basic blood testsBritish Journal of Haematology · 2026
16. BRIDGE-AD reveals Alzheimer’s disease effectors through interpretable large-scale omics integration2026
17. Analysis of the expression of genes encoding the endothelin signaling pathway in fetal, healthy and diseased adult human heart using single-cell transcriptomicsCanadian Journal of Physiology and Pharmacology · 2026
18. A phase IIa study of the anti‐ PD ‐ L1 antibody avelumab in relapsed/refractory PTCL : The AVAIL ‐T trialBritish Journal of Haematology · 2026
19. Platelet derived small extracellular vesicles are cardioprotective in murine myocardial infarctionScientific Reports · 2026
20. Rare Hematopoietic Stem Cells resilient to infection-induced stress sense yet withstand inflammationBlood · 2026