Research Institute for Fragrance Materials

Recent papers from Research Institute for Fragrance Materials

1. A proposed evaluation of new approach methodologies for dermal toxicity assessment of botanicalsPharmaceutical Biology · 2026
2. Updates to the RIFM Criteria Document for fragrance ingredient evaluationFood and Chemical Toxicology · 2026
3. A screening strategy for identifying the developmental and reproductive toxicity potential of botanicals.2026
4. Integrating new habits and practices data and homecare products into the Creme RIFM aggregate exposure modelRegulatory Toxicology and Pharmacology · 2026
5. Derivation of a Point of Departure using NAMs for application in Quantitative Risk Assessment of fragrance materialsRegulatory Toxicology and Pharmacology · 2026
6. Evidence integration in TSCA risk evaluation: The value of tiered risk assessment – A case study using HHCBRegulatory Toxicology and Pharmacology · 2026
7. Assessing the skin sensitization potential of fragrance ingredients in consumer products using the peroxidase peptide reactivity assay (PPRA) as an additional weight of evidenceToxicology in Vitro · 2026
8. The way forward for assessing the human health safety of cosmetics in the EU: Proceedings of Workshop 2Archives of Toxicology · 2026
9. Advancing chemical grouping: development and application of signature-based structure-activity groups for non-animal safety assessmentsComputational Toxicology · 2025
10. Quantitative next generation risk assessment for skin sensitization - application of regression models based on in vitro data to estimate point of departureRegulatory Toxicology and Pharmacology · 2025
11. Applicability Domain of Peroxidase Peptide Reactivity Assay (PPRA): Chemical Structure Analysis and Grouping of Peptide Depletion PatternsChemical Research in Toxicology · 2025
12. Aquatic Risk of Fragrance Materials: Advancing Prioritization in Aquatic SystemsEnvironmental Toxicology and Chemistry · 2025
13. Chemical Profiling of Volatile and Non‐Volatile Fractions of Galbanum (Ferula galbaniflua Boiss.) Used in PerfumeryChemistry & Biodiversity · 2025
14. Real-World Quantitative Insights into the Treatment Experience of Patients with Cancer in the USA with Subcutaneous Versus Intravenous Drug DeliveryOncology and Therapy · 2025
15. Use of NAMs in a weight of evidence approach to evaluate the safety via the inhalation route of acetylated vetiver oil, in spray productsRegulatory Toxicology and Pharmacology · 2025
16. The Chicken Egg Genotoxicity Assay (CEGA): Assessing Target Tissue Exposure and Metabolism in the Embryo‐Fetal Chicken LiversEnvironmental and Molecular Mutagenesis · 2025
17. Update to RIFM fragrance ingredient safety assessment, benzyl valerate, CAS Registry Number 10361-39-4Food and Chemical Toxicology · 2025
18. Update to RIFM fragrance ingredient safety assessment, amyl hexanoate, CAS registry number 540-07-8Food and Chemical Toxicology · 2025
19. RIFM fragrance ingredient safety assessment, ethyl maltol, CAS Registry Number 4940-11-8Food and Chemical Toxicology · 2025
20. RIFM fragrance ingredient safety assessment, nonyl alcohol, CAS Registry Number 143-08-8Food and Chemical Toxicology · 2025