Benaroya Research Institute

Recent papers from Benaroya Research Institute

1. T–B interactions yield CD3 + B cells and CD20 + T cells with pathogenic features in multiple sclerosisProceedings of the National Academy of Sciences · 2026
2. Somatic epimutations cap genetic determinism in the human diploid chromatin epigenomeCell · 2026
3. Candida in the lower respiratory tract induces barrier disruption in mice and predicts poor outcomes in mechanically ventilated humansProceedings of the National Academy of Sciences · 2026
4. IL-2 mutein selectively expands thymic memory Tregs with increased transendocytosis activity in healthy participantsJCI Insight · 2026
5. International consensus guidance for general population screening for islet autoantibodies to diagnose early-stage type 1 diabetes: a nominal group technique processDiabetologia · 2026
6. Reprogramming engineered autologous T cells to overcome resistance in patients with Merkel cell carcinomaScience Translational Medicine · 2026
7. Specificity, frequency, and phenotype of citrullinated-specific T cells vary with disease activity in rheumatoid arthritisJCI Insight · 2026
8. Distinct Gene Expression Profiles of Ara h 2‐Specific B Cells in Desensitization and Tolerance During Peanut Oral ImmunotherapyAllergy · 2026
9. Research agenda and related workforce requirements inspired by Lived Experience Experts and grounded in health equity for the Bleeding Disorders Research CollaborativeExpert Review of Hematology · 2026
10. Comprehensive Biomarker Strategy to Monitor GNTI-122, an Engineered Regulatory T Cell Therapy in Clinical Development to Treat Type 1 Diabetes 2252996The Journal of Immunology · 2026
11. Loss of αVβ6 integrin function disrupts intestinal immune homeostasis and increases susceptibility to experimental colitis 2310140The Journal of Immunology · 2026
12. GM-CSF-IRF5 Axis as a Therapeutic Target in TLR7-Mediated Macrophage Activation Syndrome 2309192The Journal of Immunology · 2026
13. Spatially resolved gene programs and cell neighborhoods of scleroderma fibroblasts 2261024The Journal of Immunology · 2026
14. Structural Rewiring of TCR Docking by Protective HLA Alleles Drive Treg-Mediated Tolerance in Type 1 Diabetes 2255268The Journal of Immunology · 2026
15. High Resolution Single-Cell Epigenetic Atlas of Immune Cell Types Reveals Gene Regulatory Circuits in Healthy Humans 2308992The Journal of Immunology · 2026
16. Defects in CD8+ T cell suppression by Foxp3-dE2 regulatory T cells 2257749The Journal of Immunology · 2026
17. Anti-integrin autoantibodies associated with ulcerative colitis inhibit mucosal TGF-beta activation 2309966The Journal of Immunology · 2026
18. Plasma proteomics reveals shared biologic signatures of acute respiratory failure across etiology and severity in COVID-19 and non-COVID-19 cohortsCommunications Medicine · 2026
19. Mapping of class II HLA restriction of SepSecS-specific CD4 T-cell epitopes in autoimmune hepatitisJHEP Reports · 2026
20. A head-to-head comparison of abatacept and adalimumab in adults with early and dual seropositive rheumatoid arthritis plus HLA-DRB1 shared epitope: results from the randomised phase 3 AMPLIFIED trialAnnals of the Rheumatic Diseases · 2026