Institute of Bioinformatics

Recent papers from Institute of Bioinformatics

1. DoAggregate: a pipeline for aggregation testing for rare-variant on a gene and pathway level2026
2. Susceptibility and cellular responses of COPD airway epithelium to cigarette smoke in stem cell-derived ALI models2026
3. An integrated database of ion channels2026
4. Second-Derivative IR Spectroscopy Reveals Hidden Modes of Structural Organization within Conformational DisorderAnalytical Chemistry · 2026
5. N-linked glycoproteomic and proteomic characterization of esophageal squamous cell carcinoma cell linesDiscover Oncology · 2026
6. DyME: An MD-based engine exploiting HTP mutagenesis for protein engineering and recognition mimicryPLoS Computational Biology · 2026
7. Untargeted LC–MS–Based Metabolomics Reveals Metabolic Fate and Cellular Biochemical Disruptions Induced by 4,4‐Diaminodiphenylmethane in Human Skin FibroblastsJournal of Applied Toxicology · 2026
8. Antimicrobial resistance in functional fruits-associated lactic acid bacteria within agri-food systemsFood Safety and Risk · 2026
9. In-silico personalized protein–protein interaction networks prioritize candidate compounds for glioblastomaPLoS Computational Biology · 2026
10. Unraveling the epidemiological and dispersal dynamics of the 2024–2025 chikungunya virus epidemic on Réunion IslandProceedings of the National Academy of Sciences · 2026
11. Factors associated with prior pregnancy loss among multigravid women: a retrospective machine learning analysis from an African population cohortFrontiers in Global Women s Health · 2026
12. Structural biology of the TRPM4 channel: architecture, modulation, and therapeutic opportunitiesFrontiers in Pharmacology · 2026
13. Adopting graph-based pangenomics for agronomy and biodiversity studies: current resources and challengesPeer Community Journal · 2026
14. Assessing the pathogenic potential of PIK3CA gene variants in human cancer using a computational approachJournal of Biomolecular Structure and Dynamics · 2026
15. Hex -MASP for mapping the whole-tissue spatial proteome and the intrabrain distribution of monoclonal antibodiesProceedings of the National Academy of Sciences · 2026
16. Gene-sharing networks and evolutionary modules define the genetic landscape of Shigella bacteriophagesBiology Direct · 2026
17. Octopamine receptors in Drosophila larvae: expression, development, and behaviorFrontiers in Molecular Neuroscience · 2026
18. Synthesis, Anticancer Evaluation, mRNA Expression Analysis, and Molecular Docking of Fluorinated Picolinamide–Benzothiazole Derivatives Against Breast Cancer‐Related Genes CDK2, ERK2, and BCL2Journal of Biochemical and Molecular Toxicology · 2026
19. Reduced IP6K levels impair life-cycle transitions and intracellular development of Trypanosoma cruzi within human cardiomyocytesCommunications Biology · 2026
20. Systems biology analysis reveals miRNA–mRNA networks associated with cardiomyocyte responses to SARS-CoV-2 infectionnpj Systems Biology and Applications · 2026