Merck (Japan)

Recent papers from Merck (Japan)

1. Development of a ready-to-use cell-based functional neutralizing antibody assay for MK-1484, a PEGylated IL-2 mutein that preferentially activates effector T-cellsBioanalysis · 2026
2. Vaccine Ligand Binding Assay DevelopmentBioanalysis · 2026
3. Acoustic Droplet Ejection High-Resolution Mass Spectrometry Enables High-Throughput Analysis of Proteins in Complex Biologic and Vaccine MatricesAnalytical Chemistry · 2026
4. Pharmacological Evaluation of TSLP Dependency in Preclinical Asthma Models 2246596The Journal of Immunology · 2026
5. Real‐World Use of Avelumab First‐Line Maintenance for Locally Advanced or Metastatic Urothelial Carcinoma in Japan: Treatment Patterns, Effectiveness, and SafetyInternational Journal of Urology · 2026
6. Double Deoxygenative Coupling of Carboxylic Acids and AlcoholsACS Catalysis · 2026
7. An exploratory study to determine the feasibility and processes needed to implement the Immunization Neighborhood to increase HPV vaccination among African American adolescents and adolescents in the general population: A multi-partner perspectiveHuman Vaccines & Immunotherapeutics · 2026
8. Assessing the Accuracy and Reliability of the Swine Sense Hub® Camera for Estimating Body Weights of Individual Growing PigsJournal of Animal Science · 2026
9. Vaccine Ligand Binding Assay Life Cycle Management, Assay Maintenance, Monitoring and TransferBioanalysis · 2026
10. Cost of care and budget impact of novel first-line treatments in patients with locally advanced or metastatic urothelial carcinoma from the Colombian healthcare system perspectiveExpert Review of Pharmacoeconomics & Outcomes Research · 2026
11. 2025 White Paper on Recent Issues in Bioanalysis: What is the Future of Bioanalytical LIMS? AI/ML Integration in Bioanalysis; Tear Sample Collection; Radiolabeled Mass Balance Studies; Chiral Assays; Bioanalysis of Antibody-Oligonucleotide & Bicycle Drug Conjugates ( PART 1A – Recommendations on Mass Spectrometry Assays, Chromatography, Sample Preparation and Regulated Bioanalysis Sampling, Validating, Analyzing & Reporting PART 1B – Regulatory Agencies’ Input on Regulated Bioanalysis/BMV)Bioanalysis · 2026
12. 2025 White Paper on Recent Issues in Bioanalysis: Biomarkers Calibrators & Stability; Evaluation of NULISA; Neurofilament & Autoantibody Biomarker Assays; Removing IgM Interference; ELISpot & FluoroSpot Best Practices; Modular HD Cytometry; Single-cell Analysis Imaging Cytometry (PART 2A – Recommendations on Biomarkers Discovery, Development, Validation & Regulatory Approval, Ligand-Binding Assays (LBA) and Cell-Based Assays (CBA) PART 2B – Regulatory Agencies’ Input on Biomarkers, IVD/CDx and Biomarker Assay Validation (BAV))Bioanalysis · 2026
13. Considerations on Interim Evaluation of OS in Pivotal Oncology TrialsStatistics in Biopharmaceutical Research · 2025
14. Scalable Electrochemical Preparation of Spermidine and SpermineACS electrochemistry. · 2025
15. JAVEMACS-D: claims database analysis of avelumab maintenance therapy for advanced urothelial carcinoma in JapanScientific Reports · 2025
16. JAVEMACS: a real-world study of avelumab maintenance therapy for advanced urothelial carcinoma in JapanESMO Real World Data and Digital Oncology · 2025
17. Insomnia disorder and cerebrospinal fluid markers of dementiaJournal of Alzheimer s Disease · 2025
18. Dual-Criterion Dose Finding Designs Based on Dose-Limiting Toxicity and TolerabilityStatistics in Biopharmaceutical Research · 2025
19. Process Safety in the Pharmaceutical Industry─Part III: Dust Hazard EvaluationOrganic Process Research & Development · 2025
20. ADAPT-M: A workflow for rapid, quantitative in vitro measurements of enriched protein libraries2025