Hopp Children's Cancer Center Heidelberg

Recent papers from Hopp Children's Cancer Center Heidelberg

1. Rapid proteasomal degradation of mutant feline McDonough sarcoma-like tyrosine kinase-3 overcomes inhibitor resistance mechanisms of acute myeloid leukemia cellsLeukemia · 2026
2. Standard treatment against paediatric BRAF-V600E glioma promotes senescence and sensitizes tumours to BCL-xL inhibitionNeuro-Oncology · 2026
3. Identification and characterization of a novel distinct Pineal Neoplasm with Neuroendocrine and Epithelial Differentiation (PINNED)Acta Neuropathologica · 2026
4. Cytotoxic activity of selinexor in BRAFV600E-driven pediatric low-grade glioma 3D culturesActa Neuropathologica Communications · 2026
5. Selpercatinib in Pediatric and Adolescent Patients With RET -Altered Solid Tumors: Safety and Efficacy Results From the Phase I/II LIBRETTO-121 StudyJournal of Clinical Oncology · 2026
6. Familial Cancers Associated With Cancers of the Breast, Prostate, Colorectum, and Lung in SwedenInternational Journal of Cancer · 2026
7. Globalising the access to advanced molecular diagnostics of CNS tumors: Experience of the Molecular Neuro-Pathology (MNP) Outreach ConsortiumNeuro-Oncology · 2026
8. Targeting CD28 on T lineage malignancies with chimeric antigen receptor T cellsNature Communications · 2026
9. Three‐generation familial risks in early‐onset prostate cancer with maternal and paternal relativesBJU International · 2026
10. Co-expression of non-signaling CARs enhances EGFRvIII-specific CAR T-cell cytotoxicity against head and neck squamous cell carcinomaBMC Cancer · 2026
11. Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependencyNature Genetics · 2026
12. Functional proteomic and phosphoproteomic profiling of routine FFPE CNS tumor tissue complements genomic and epigenomic characterizationActa Neuropathologica · 2026
13. Interdisciplinary management and genetic evaluation of pediatric cancer predisposition syndromes: a retrospective cohort studyEuropean Journal of Human Genetics · 2026
14. Clinical efficacy/effectiveness, safety, and health-related quality of life associated with relapsed/refractory pediatric low-grade glioma treatments: systematic literature reviewNeuro-Oncology Pediatrics · 2026
15. Immune checkpoint knockout screen reveals TIGIT-CD155 interaction as a significant modulator of adapter CAR-T cell function in acute myeloid leukemiaOncoImmunology · 2026
16. Parvovirus B19 infections in paediatric sickle cell disease patients: Genotype and hydroxyurea treatment influence disease severityBritish Journal of Haematology · 2026
17. O-mannosylation and protein maturation checkpoints represent therapeutic opportunities in BRAF fusion protein oncogenesisCancer Discovery · 2026
18. Efficacy and safety of proton radiotherapy for progressive or surgically unfavorable adult pilocytic astrocytoma: a single-center experienceJournal of Neuro-Oncology · 2026
19. Cancer control after pausing treatment with larotrectinib in responding children with sarcoma and a TRK fusion: a plain language summaryFuture Oncology · 2026
20. Molecular characterization of mismatch repair deficient tumors in young Jordanian patientsDiscover Oncology · 2026