Tri-Institutional PhD Program in Chemical Biology

Recent papers from Tri-Institutional PhD Program in Chemical Biology

1. How Many Crystal Structures Do You Need to Trust Your Docking Results?Journal of Medicinal Chemistry · 2026
2. Diisonitrile Chalkophore Structure and Function in Mycobacterial Copper AcquisitionJournal of the American Chemical Society · 2026
3. Systematic identification of p11 as a signaling modulator across the GPCRomeScience Advances · 2026
4. Senescence-directed nanotherapy ameliorates fibrosis and overcomes immune exclusion in cancerScience · 2026
5. Functional characterization of viral transcriptional regulators reveals extensive rewiring of host pathwaysNature Communications · 2026
6. Type 1 interferon perturbates clonal competition by reshaping human blood developmentNature Genetics · 2026
7. Configurational diversity of metabotropic glutamate receptor complexes with beta-arrestinsNature Communications · 2026
8. Structural basis of active state coupling of metabotropic glutamate receptor 8 to beta-arrestinsNature Communications · 2026
9. Linker Histone H1 Phosphorylation Promotes DNA Damage Repair during Replication StressACS Chemical Biology · 2026
10. MtvS1 and MtvS2 Interact with RNA polymerase to regulate the Francisella type V-A CRISPR-Cas systemNature Communications · 2026
11. Disrupted glucocorticoid rhythms selectively induce severe skeletal muscle insulin resistance and uncouple obesity from hepatic steatosisCell Reports · 2026
12. Role of orphan G protein-coupled receptor GPR52 in breast cancer cell multicellular organization and collective invasionBritish Journal of Cancer · 2026
13. Load to Failure for a Novel Scapholunate Bridge Augmentation TechniqueJournal of Wrist Surgery · 2026
14. Profiling the aromatic amino acid metabolome in the human gut microbiota reveals Clostridioides difficile -specific N -acyl amino acidsmSystems · 2026
15. Developmental reversion underlies resistance to immune checkpoint blockade in kidney cancer2026
16. FAF1 cofactor enhances UFD1/NPL4-p97 unfolding efficiency across ubiquitin chain lengths independent of SUMO22026
17. Single-cell multimodal profiling of pan-cancer cell lines uncovers gene regulatory principles underlying intrinsic cell states and environmental featuresNature Communications · 2026
18. The bacterial mechanosensitive channel MscM gates through concerted changes in its transmembrane and cytoplasmic domainsNature Communications · 2026
19. PLA2G2F suppresses ferroptosis through phospholipid remodelingNature Structural & Molecular Biology · 2026
20. Ensembles of in silico structures enable T cell peptide-MHC binding prediction2026