Model Animal Research Center

Recent papers from Model Animal Research Center

1. Integrative genomics and regulomics reveal the molecular architecture of complex traits in domestic chickensiMeta · 2026
2. The mechanosensitive channel TMEM63B contributes to noxious heat sensation in the dorsal root gangliaPLoS Biology · 2026
3. DHHC12 serves as a critical nutrient-responsive switch that couples amino acid sensing to insulin secretionNature Communications · 2026
4. The postantibiotic effect-like effect of photothermal agents: evidence from IR780 nanoparticles and indocyanine greenFrontiers in Pharmacology · 2026
5. Pangolin-derived sarbecoviruses show attenuated pathogenicity and transmissibility than SARS-CoV-2 in human ACE2 transgenic hamstersmBio · 2026
6. Inhibition of neuronal DICER–miR-34a/346 signaling attenuates amyloid pathology in 5×FAD miceAlzheimer s Research & Therapy · 2026
7. Integrative multi-omics landscape and diagnostic-therapeutic modelling of steatohepatitic hepatocellular carcinomaGut · 2026
8. Baseline Cortisol and Behavioral Phenotype Are Linked to Context‐Dependent Spatial Cognition and Space Use in Giant PandasIntegrative Zoology · 2026
9. Coronavirus Nsp5‑mediated dual‑site cleavage of GSDMA modifies its antiviral and proinflammatory functionsPLoS Pathogens · 2026
10. AND-gated dual-responsive nanogels for spatiotemporally controlled codelivery of a PPARδ antagonist and anti-PD-1 antibodyJournal of Nanobiotechnology · 2026
11. Oligodendrocyte‐Targeted SGK1.1 Inhibition Alleviates White Matter Injury and Cognitive Impairment in Alzheimer's Disease via Modulation of HDAC2 PhosphorylationCNS Neuroscience & Therapeutics · 2026
12. Targeting the GPR183/EBI2‒oxysterol axis in tuberculosis: Immunometabolic regulation and prospects for host‐directed therapyClinical and Translational Medicine · 2026
13. Jer1–Ga2–LpR1 axis mediates upstream input of alpha-mannosidosisJournal of Molecular Cell Biology · 2026
14. The cellular and molecular basis of gyrus-sulcus specialization in the primate brainNature Communications · 2026
15. Functionally cured chronic hepatitis B: A cure‐related occult HBV infection statemLife · 2026
16. Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell ImmunityAdvanced Science · 2026
17. YTHDC1 functions as a molecular chaperone to suppress ALS-linked hnRNPA1 mutants from aggregationNature Communications · 2026
18. A novel LepR knockout hamster model for type 2 diabetes and its complications: a complementary platform to conventional rodent modelsFrontiers in Endocrinology · 2026
19. Hypoxia-Stabilized HIF1α Restricts Hair Cell Reprogramming by Suppressing Wnt Signaling in the Mammalian CochleaCells · 2026
20. Comparative testicular transcriptomic analysis reveals hub genes and pathways regulating semen quality in Zhedong white ganders (Anser cygnoides)Frontiers in Veterinary Science · 2026