Parker Institute for Cancer Immunotherapy

Recent papers from Parker Institute for Cancer Immunotherapy

1. Compartment-specific PPARδ activity controls the outcome of cancer–immune cell competition and immunotherapy efficacyNature Immunology · 2026
2. Immune biomarkers of response and resistance to ipilimumab and nivolumab in metastatic castration-resistant prostate cancerScience Advances · 2026
3. Standardizing Cell Ontology terms for cross-study integration in the female reproductive tractScience Advances · 2026
4. z‐VAD‐FMK triggers macrophage necroptosis during mycobacterial infection via a non‐canonical off‐target mechanismmLife · 2026
5. Development and Validation of an Ultra-low-cost, Open-source Normothermic Ex Vivo Organ Perfusion PlatformTransplantation · 2026
6. Brain-Resident Memory T Cells: Cellular Mechanisms and Engineering Perspectives in Neuroimmune SurveillanceCellular and Molecular Bioengineering · 2026
7. T-cell lymphoma following chimeric antigen receptor-T therapy: a cause for concern?Haematologica · 2026
8. Regulation of immune signal integration and memory by inflammation-induced chromosome conformationProceedings of the National Academy of Sciences · 2026
9. Clonal stochasticity in early NK cell response to mouse cytomegalovirus is generated by mature subsets of varying proliferative abilityeLife · 2026
10. Comparing bulk and single-cell methodologies and models to profile gene expression, chromatin accessibility and regulatory links in endothelial cells treated with TNFαBiochemistry and Biophysics Reports · 2026
11. Reprogramming engineered autologous T cells to overcome resistance in patients with Merkel cell carcinomaScience Translational Medicine · 2026
12. Programmable CAR-engaging particles rewire human CAR T-cell signaling for sustainable ex vivo expansionNature Communications · 2026
13. Impaired regulation by purinergic signaling axis contributes to CD8+ T cell dysregulation in STAT3 gain of functionJCI Insight · 2026
14. Neoadjuvant PD1 plus CTLA-4 immune checkpoint blockade in surgically resectable recurrent glioblastoma: a randomized surgical window-of-opportunity trialNature Communications · 2026
15. Metabolomics of in vivo inflammation identifies soluble sialic acid as a conserved myeloid-cell metaboliteJournal of Biological Chemistry · 2026
16. CD94-targeted depletion reduces NK cells and attenuates mouse kidney ischemia-reperfusion injury and subsequent acute lung injuryAmerican Journal of Transplantation · 2026
17. FAP-Directed CAR-NKT Cells for Multi-Target Suppression of Atherosclerotic ProgressionCirculation Research · 2026
18. Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of InflammationAngewandte Chemie · 2026
19. HisToSpatialCNV: an interpretable deep learning method predicting spatial copy number variations from histopathology imagesNature Biomedical Engineering · 2026
20. Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of InflammationAngewandte Chemie International Edition · 2026