Institut du Fer à Moulin

Recent papers from Institut du Fer à Moulin

1. NKCC1 coordinates SPAK-PP1 signalling to regulate KCC2 membrane stability and seizure susceptibility.2026
2. Epileptic encephalopathy-related Kv2.1 mutants impair clustering but not neuronal excitabilityBiophysical Journal · 2026
3. WNK-dependent phosphorylation of gephyrin tunes GABA A receptors at inhibitory synapses and modulates anxiety behaviorProceedings of the National Academy of Sciences · 2026
4. Explainable boosting machine for predicting claim severity and frequency in car insuranceEuropean Actuarial Journal · 2026
5. Glycosylation-independent functions for distinct glypican core proteins drive cell-specific responses in corticogenesisProceedings of the National Academy of Sciences · 2026
6. Correction: Frau et al. A New Ammonite Biostratigraphic Framework for Distal Urgonian Successions of North Provence and a Correlation with Southern Vercors. Diversity 2026, 18, 162Diversity · 2026
7. Pyk2 plays a critical role in synaptic dysfunction during the early stages of Alzheimer’s diseaseMolecular Neurodegeneration Advances · 2026
8. Enhancing KCC2 function reduces interictal activity and prevents seizures in temporal lobe epilepsyProceedings of the National Academy of Sciences · 2026
9. The serotonin receptor 2b (5-HT2B) modulates heart remodeling following myocardial infarction via regulation of Hippo pathwayiScience · 2026
10. Differential isoform-specific control of KCC2 function in developing cortical neurons2026
11. Ablation of the D1 Dopamine Receptor Alters the Migration and the Cortical Distribution of MGE‐Derived Inhibitory Interneurons by a Preponderant Non–Cell‐Autonomous EffectEuropean Journal of Neuroscience · 2026
12. Molecular basis and cellular effects of Janus-class–driven cytoplasmic PYK2 coacervatesCommunications Biology · 2026
13. Organelle distribution and protein translation defects in radial glia cells with mutations in Eml12025
14. Modulation of striatal cAMP levels: A key pathway in the treatment of hyperkinetic movement disordersiScience · 2025
15. Broad transcriptomic effects of Egr1 knockdown in the mouse nucleus accumbens core and its role in cocaine locomotor sensitizationProgress in Neuro-Psychopharmacology and Biological Psychiatry · 2025
16. BDNF exerts an NRF2-dependent cytoprotective function via a receptor-independent pathwayCell Reports · 2025
17. Capturing disease severity in LIS1-lissencephaly reveals proteostasis dysregulation in patient-derived forebrain organoidsNature Communications · 2025
18. Fundamental Neurochemistry Review: Sphingolipids and Ceramides in Brain DevelopmentJournal of Neurochemistry · 2025
19. The ciliary kinesin KIF7 controls the development of the cerebral cortex by acting differentially on SHH signaling in dorsal and ventral forebraineLife · 2025
20. WNK-Dependent Phosphorylation of Gephyrin Tunes GABAA Receptors at Inhibitory Synapses and Modulates Anxiety Behavior2025