NIHR Newcastle Biomedical Research Centre

Recent papers from NIHR Newcastle Biomedical Research Centre

1. Validation of the mobgap analytical pipeline for estimation of digital mobility outcomes from a single wearable device across all-cause dementia and discrete dementia disease subtypesJournal of NeuroEngineering and Rehabilitation · 2026
2. Health-care burden of metabolic dysfunction-associated steatotic liver disease in European tertiary-care outpatient clinics (CONSTANS): a prospective multicentre cohort studyThe Lancet Regional Health - Europe · 2026
3. Diagnostic accuracy of MRI-derived imaging biomarkers and machine learning-based classification in distal and myofibrillar myopathiesEuropean Radiology · 2026
4. Qualitative analysis of staff views on caring for inpatients with delirium and Parkinson's disease: Challenges, tensions and team workingJournal of Parkinson s Disease · 2026
5. A Recurrent 3′ UTR Variant in CAPN3 Highlights the Diagnostic Impact of Non‐Coding Variants in Limb‐Girdle Muscular DystrophiesAnnals of Neurology · 2026
6. Characterization of a novel homozygous CTLA4 variantJournal of Human Immunity · 2026
7. A phase 2b randomized clinical trial of the oral p38α inhibitor neflamapimod in dementia with Lewy bodies (DLB)Alzheimer s Research & Therapy · 2026
8. Front-line decision-making: a thematic analysis of interviews with hospital staff on referrals, admissions, and care for people with multiple long-term conditionsBMC Medicine · 2026
9. ‘People need to be a bit more understanding that my body is wrecked’: A qualitative exploration of inpatient hospital care for people living with multiple long-term conditionsBMC Medicine · 2026
10. Obesity partly explains the effect of socioeconomic position on multiple long-term conditions in UK BiobankScientific Reports · 2026
11. Hepatic manifestations of ciliopathies: genetic causes and clinical updateEuropean Journal of Pediatrics · 2026
12. Meaningful digital mobility outcomes for people with Parkinson's disease: Insights grounded in diverse lived experienceJournal of Parkinson s Disease · 2026
13. Mapping equity-relevant inputs of AI mental health tools to routine primary care data: a population-based study of 7.19 million adults with multiple long-term conditions in EnglandBMC Psychiatry · 2026
14. Expanding the Phenotypic Spectrum of TXNDC15 ‐Related Ciliopathies to Include Joubert SyndromeAmerican Journal of Medical Genetics Part A · 2026
15. GLP-1 receptor agonists—a potential therapy for chronic kidney disease?Clinical Science · 2026
16. Target product profiles in laboratory medicine: a framework for defining test requirements and supporting outcome-based performance specificationsClinical Chemistry and Laboratory Medicine (CCLM) · 2026
17. Modeling Framework for Economic Evaluation of Disease-Modifying Therapies in Parkinson’s Disease: Evidence Review and Expert OpinionPharmacoEconomics · 2026
18. Medication Appropriateness and Potentially Inappropriate Medications in Older Critical Care Patients: A Scoping ReviewDrugs & Aging · 2026
19. Spatially resolved multiomics of human meningeal development reveal lineage and disease dynamicsNature Cell Biology · 2026
20. Treatment‐driven peripheral blood transcriptomic remodelling and baseline predictors of ESSDAI and STAR response to B‐cell therapy in Sjögren's diseaseArthritis & Rheumatology · 2026