Innovative Genomics Institute

Recent papers from Innovative Genomics Institute

1. CRISPR-dPCR: A unified multiplex digital PCR framework for quantitative characterization of targeted knock-in2026
2. When DNA methylation integrity fails: Lessons from plant aging and tissue cultureCurrent Opinion in Plant Biology · 2026
3. Identification and genetic characterization of megabase-scale plasmids of EnterobacteriaceaeNature Communications · 2026
4. Weathering-derived calcium supports carbon storage in grassland soilsCommunications Earth & Environment · 2026
5. Structural insights into the coupling mechanism of vectorial CO 2 uptake by DAB1Proceedings of the National Academy of Sciences · 2026
6. A membrane-free spot-plating protocol for Agrobacterium-mediated transformation of diverse yeastsPLoS ONE · 2026
7. Signaling by a tyrosine-sulfated peptide balances growth and osmotic stress response in riceProceedings of the National Academy of Sciences · 2026
8. Diagnostic yield of genome sequencing for children with intellectual disability and developmental delayFrontiers in Neurology · 2026
9. mTORC1 drives cell-autonomous astrocyte reactivity in tuberous sclerosisNature · 2026
10. Peptide-mediated CRISPR delivery: From dish to bloodstreamCurrent Opinion in Chemical Biology · 2026
11. VIPR RNA-guided DNA recognition by noncontiguous geometric triplex formationScience · 2026
12. A noncontiguous code for RNA-guided DNA recognition at the origin of CRISPR-CasScience · 2026
13. Active learning enables evolutionary discovery and characterization of fungal transcriptional activatorsGenome biology · 2026
14. Visualizing synaptic disruptions in the release and regulation of dopamine hotspots in Huntington’s DiseaseJournal of Neuroscience · 2026
15. Chemically modified CRISPR enzymes for multi-organ genome editing in vivo2026
16. Engineered Orthogonal Translation Systems from Metagenomic Libraries Expand the Genetic CodeACS Synthetic Biology · 2026
17. Telomere length of both parents contributes to heritable POT1 cancer-predisposition syndromeNature Communications · 2026
18. Charge-switching ionizable lipids lower the toxicity of lipid nanoparticlesNature Nanotechnology · 2026
19. Chemogenomic maps reveal a PRDX1-dependent iron–damage axis in the DNA damage responseNature Chemical Biology · 2026
20. Predicting genome-wide functional constraints with GPN-StarNature · 2026