Frankfurt Cancer Institute

Recent papers from Frankfurt Cancer Institute

1. Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1 , Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma modelsFEBS Open Bio · 2026
2. Psychological (in)flexibility as a mediator between resilience and psychological outcomes in patients with cancerScientific Reports · 2026
3. Organ Preservation and Quality of Life After Total Neoadjuvant Treatment in Rectal CancerJAMA Network Open · 2026
4. NRF2: sensing stress, shaping immunity - keeping inflammation quiet and antigens out of sightFrontiers in Pharmacology · 2026
5. Study protocol: a phase II study of trifluridine/tipiracil plus liposomal irinotecan as second-line therapy in advanced biliary tract cancer (TRITICC 2)BMC Cancer · 2026
6. Distinct Molecular Pathways Driving Thymic and Pulmonary Neuroendocrine Neoplasms: Organ of Origin Defines Molecular Identity and Yields CD44 as a Marker of Pulmonary Neuroendocrine TumorsEndocrine Pathology · 2026
7. DHODH is the key target of the KDM4 inhibitor QC6352 in glioblastoma stem cellsNature Chemical Biology · 2026
8. Visual extraction of individual patient data from published kaplan-meier survival plots using a web-based application offering different reconstruction methods (V-Exploder)BMC Medical Research Methodology · 2026
9. Global Landscape of Clinical Studies Open to Enrollment in Carbon Ion Radiotherapy: A PTCOG ReviewInternational Journal of Particle Therapy · 2026
10. Real-World First-Line Treatment Characteristics and Physician Drivers in Advanced/Metastatic Non–Small Cell Lung Cancer, PD-L1 ≥ 50%, and without Actionable Genomic AlterationsOncology and Therapy · 2026
11. Dual-Foundation-Model Ensemble Predicts Gene Expression in Muscle-Invasive Bladder Cancer for Patient Outcome StratificationModern Pathology · 2026
12. Age-associated loss of lymphatic vessels promotes cardiac inflammationNature Cardiovascular Research · 2026
13. Decreased FSP1 expression under chronic hypoxia sensitizes human macrophages towards ferroptosisRedox Biology · 2026
14. Prognostic significance of intermediate and high SUVmax values and imaging timing on FDG-PET/CT after radiation therapy in HNSCC: a retrospective cohort studyFrontiers in Oncology · 2026
15. Trends in radiation oncology between 2015 and 2022: report from a German university radio-oncology departmentStrahlentherapie und Onkologie · 2026
16. High-content imaging workflow for single-cell drug response profiling of acute myeloid leukemia subtypesSLAS DISCOVERY · 2026
17. Sleep duration links to biological aging clocks: when sleep gets tough, aging gets goingSignal Transduction and Targeted Therapy · 2026
18. Isoform‐Selective Targeting of Akt Through Covalent Allosteric InhibitionAngewandte Chemie International Edition · 2026
19. Outcomes of elderly patients treated with chemoradiotherapy for anal squamous cell carcinoma: a multicenter study of the German cancer consortium - radiation oncology group (DKTK-ROG)Clinical and Translational Radiation Oncology · 2026
20. Atezolizumab in early triple-negative breast cancer: the randomized phase 3 NSABP B-59/GeparDouze trialNature Medicine · 2026