Centre National de Recherche en Génomique Humaine

Recent papers from Centre National de Recherche en Génomique Humaine

1. Convergent genetic and functional evidence implicate KCND3 in Brugada Syndrome2026
2. Decoding Atheroprotection in Familial Hypercholesterolemia: The Role of Polygenic BackgroundAtherosclerosis · 2026
3. Epigenome-wide association study and functional analyses reveal regulatory loci linked to lung function and diabetes in cystic fibrosisRespiratory Research · 2026
4. Sympatric European white oaks species display contrasting epigenetic response to soil water availabilityTree Physiology · 2026
5. Deep molecular profiling of lung neuroendocrine tumours and supra-carcinoidsMolecular Cancer · 2026
6. Five-layer systems analysis of Leishmania stage differentiation reveals an essential role for protein degradation in parasite developmenteLife · 2026
7. scROMA: batch-aware pathway-activity inference and a ground-truth simulation framework for single-cell transcriptomics2026
8. Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease RiskAnnals of Neurology · 2026
9. Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer riskThe American Journal of Human Genetics · 2026
10. Adverse and adaptive placental DNA methylation changes linking prenatal air pollution exposure to child lung function: findings from the SEPAGES cohortEBioMedicine · 2026
11. Genetic introgression and transcriptomic plasticity are associated with enhanced Leishmania infantum pathogenicity causing human cutaneous leishmaniasis in Tunisia2026
12. Consensus meta-analysis of genome-wide association studies for Alzheimer’s disease and related dementiasNature Genetics · 2026
13. Multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycaemic traits during pregnancy reveals limited evidence of pregnancy-specific genetic effectsNature Communications · 2026
14. Assessing the de novo paradigm in sporadic early-onset Alzheimer disease triosMolecular Psychiatry · 2026
15. Integrative analysis of drug-gene signatures in human pluripotent stem cells reveals prazosin as a novel SQSTM1 regulator for ALS therapeuticsStem Cell Reports · 2026
16. Rap1-mediated steric hindrance protects telomeres from MRX sensingNature Structural & Molecular Biology · 2026
17. Post-Chornobyl thyroid papillary carcinomas display distinct past 131I exposure and radiation-associated carcinogenesis molecular signatures at low and high thyroid dosesScientific Reports · 2026
18. Genetic determinants of childhood blood pressure and heart rate in relation to adult health outcomes: the consortium of childhood blood pressureEuropean Heart Journal · 2026
19. GWAS meta-analysis of cerebrospinal fluid Alzheimer’s biomarkers reveals loci regulating lipids, brain volume and autophagyNature Communications · 2026
20. Five-layer systems analysis of Leishmania stage differentiation reveals an essential role for protein degradation in parasite developmenteLife · 2026